🗓️ Unit 12
Psychological Disorders

PSYC 181 – Intro to Psych

August 12, 2024

What you will learn

Learning Objectives

  • Describe the historical and modern approaches to mental health services and treatment

  • Understand the problems inherent in defining the concept of psychological disorder

  • Describe what is meant by harmful dysfunction

  • Identify the formal criteria that thoughts, feelings, and behaviors must meet to be considered abnormal and, thus, symptomatic of a psychological disorder

Therapy & Treatment

Treatment in the past

18th Century

Phillippe Pinel (Late 1700’s)

Dorothea Dix (19th Century)

  • Social reformer and advocate for indigent insane
  • Identified poor state of care
  • Instrumental in first American mental asylum

American Asylums (19th Century)

  • Usually filthy
  • Limited treatment
  • Individuals often institutionalized for decades

20th Century

Mental Health Treatment Today

Mental Health Treatment

  • Most not hospitalized but can still seek treatment

Involuntary treatment therapy that is not the individuals choice

  • E.g. condition of parole

Voluntary treatment the person chooses to attend therapy to obtain relief from symptoms

Types of Treatment

Psychotherapy psychological treatment that employs various methods to help someone overcome personal problems, or to attain personal growth

Biomedical therapy involves medication and/or medical procedures to treat psychological disorders

Psychodynamic psychotherapy talk therapy based on belief that the unconscious and childhood conflicts impact behavior

Play Therapy

Behavior Therapy

  • Principles of learning are applied to change undesirable behaviors

Classical Conditioning principles are applied to recondition clients and change their behavior

Counterconditioning Client learns a new response to a stimulus that has previously elicited an undesirable behavior (phobias)

Aversive conditioning uses an unpleasant stimulus to stop an undesirable behavior (addiction)

Exposure Therapy

Systematic Desensitization

  • Type of exposure therapy wherein a calm and pleasant state is gradually associated with increasing levels of anxiety-inducing stimuli

Cognitive Therapy

  • Developed by Aaron Beck in the 1960’s
  • Suggests that how you think determines how you feel and act
  • Emotional reactions are the result of your thoughts about the situation rather than the situation itself
  • Encourages clients to find more logical ways of interpreting situations and positive ways of thinking
  • Cognitive therapists help clients become aware of their cognitive distortions (thinking errors).

Cognitive-behavioral Therapy

What are psychological disorders?

Psychopathology the study of psychological disorders, including their symptoms, etiology (causes), and treatment.

DEFINITION OF A PSYCHOLOGICAL DISORDER

Psychological disorder

  • a condition characterized by abnormal thoughts, feelings, and behaviors

Cultural Expectations

  • Violating cultural expectations
    is not enough by itself
  • Social norms vary
    between cultures

American Psychological Association (APA) Definition

A psychological disorder is a condition that consists of the following:

  • Significant disturbances in thoughts, feelings, and behaviors

  • Outside of cultural norms

  • Disturbances reflect some kind of biological, psychological, or developmental dysfunction.

  • Disturbances lead to significant distress or disability in one’s life

    • E.g. difficulty performing appropriate and expected roles.

THE DIAGNOSTIC & STATISTICAL MANUAL OF MENTAL DISORDERS (DSM)

Diagnosis appropriately identifying and labeling a set of defined symptoms

  • Requires classification systems that organize psychological disorders systematically

DSM Origin Story

PREVALENCE RATES (DSM-IV)

COMORBIDITY (DSM)

perspectives on psychological disorders

SUPERNATURAL PERSPECTIVES

Disorders attributed to a force beyond scientific understanding

  • Practitioners of black magic (sorcery)
  • Possessed by spirits
  • Witchcraft

DANCING MANIA

BIOLOGICAL PERSPECTIVES

DIATHESIS-STRESS MODEL

Diathesis + Stress → Development of a disorder

Anxiety

Anxiety Disorders

SPECIFIC PHOBIA

Common Phobias

ACQUISITION OF PHOBIAS THROUGH LEARNING

  • Rachman (1977): 3 Major Learning Pathways
  1. Classical Conditioning
    • Child is bitten by dog (US) → dogs become associated with biting (CS) → child experiences fear around dogs (CR)
    • Conditioned fears develop more readily to fear-relevant stimuli (images of snakes and spiders) than to fear-irrelevant stimuli (images of flowers).
  2. Vicarious Learning
    • Child observes cousin react with fear around spiders → child later expresses the same fears even though spiders have never presented any danger to him.
  3. Verbal transmission of information
    • A child is continuously told that snakes are dangerous → child starts to fear snakes.

SOCIAL ANXIETY DISORDER

Prevalence

  • ~ 12% of Americans

Comorbidity

  • high rates alcohol abuse disorder (self-medicating)

Risk factors

  • Fears of social situations possibly developed through conditioning

  • Most report history of severe teasing in childhood

PANIC DISORDER

Prevalence

  • ~ 12% of U.S. population

Comorbidity

  • anxiety or major depressive disorders

PANIC DISORDER CAUSES

Genetics

  • 43% heritability

Neurobiological Theories

  • Locus coeruleus in the brainstem is possibly involved

  • Major source of norepinephrine (neurotransmitter that triggers flight-or-flight response)

  • Activation is associated with anxiety and fear and produces panic-like symptoms in nonhuman primates

Conditioning Theories Panic attacks are classical conditioning responses to subtle bodily sensations resembling those normally occurring when one is anxious or frightened

Cognitive Theories Individuals with panic disorder are prone to interpret ordinary bodily sensations catastrophically, setting the state for panic attacks.

  • In some patients, reducing catastrophic cognitions about sensations has proven to be as effective as medication in reducing panic attacks

GENERALIZED ANXIETY DISORDER

  • A relatively continuous state of excessive, uncontrollable, and pointless worry and apprehension.

Diagnosis Criteria

  • The diffuse worrying and apprehension is not part of another disorder.

  • Symptoms occur more days than not for at least 6 months.

  • Symptoms are accompanied by any three of the following symptoms:

    • Restlessness, difficulty concentrating, being easily fatigued, muscle tension, irritability, and sleep difficulties

Prevalence

  • Affects about 5.7% of U.S. population during their lifetime
  • Females are 2 times as likely as males to experience the disorder

Comorbidity

  • Comorbid with mood disorders and other anxiety disorders

GENERALIZED ANXIETY DISORDER CAUSES

Cognitive Theories

  • Worry represents a mental strategy to avoid more powerful negative emotions perhaps stemming from earlier unpleasant or traumatic experiences

  • Worrying acts a distraction from remembering painful childhood experiences

OBSESSIVE COMPULSIVE DISORDER (OCD)

Prevalence

  • ~ 2.3% of U.S. population

Comorbidity

  • high rates depression and anxiety disorders

Common Obsessions

  • Concerns about germs and contamination

  • Doubts

  • Order and symmetry

  • Aggressive or lustful urges

OCD CAUSES

Genetics

  • 5 times more frequent in first-degree relatives of people with OCD
  • Identical twins
  • 57% concordance rate
  • Fraternal twins - 22% concordance rate
  • Genes involved regulate the function of serotonin, dopamine, and glutamate

Conditioning Theories

  • Symptoms of OCD are learned responses resulting from both classical and operant conditioning

  • Neutral stimulus + unconditioned stimulus → anxiety or distress.

  • Once association has been acquired, encounters with the NS trigger anxiety and obsessive thoughts.

  • Anxiety and obsessive thoughts continue until a strategy is identified to relieve it

  • Relief may be ritualistic behavior or mental activity that reduces anxiety

  • Compulsive acts become negatively reinforcing.

OCD Circuit

Orbitofrontal cortex

  • involved in learning and decision making
  • Becomes hyperactive in people with OCD when provoked with tasks such as looking at photos of a toilet or a pictures hanging crookedly on a wall

BODY DYSMORPHIC DISORDER

Prevalence

  • ~ 2.4% of U.S. population
  • slightly higher rates in women than men

Comorbidity

  • high rates depression and anxiety disorders

HOARDING DISORDER

DEFINITION OF PTSD

Diagnosis Criteria

  • Individual was exposed to, witnessed, or experienced the details of a traumatic experience (“actual or threatened death, serious injury, or sexual violence”) (APA, 2013)

  • PTSD was first recognized in soldiers who had engaged in combat.

    • Symptoms occur for at least one month

Symptoms Intrusive and distressing memories of the event

  • Flashbacks – states during which individual relives the event and behaves as if it were occurring at that moment
  • Avoidance of stimuli connected to the event
  • Persistently negative emotional states
  • Feelings of detachment from others
  • Irritability
  • Proneness toward outbursts
  • Exaggerated startle response.

Prevalence Experienced by approximately 7% of the U.S. population in their lifetime.

RISK FACTORS FOR PTSD

Risk Factors

  • Trauma experience

  • Lack of immediate social support

  • Social Support (comfort, advice, and assistance from relatives, friends, and neighbors) can reduce the risk of developing PTSD

  • Subsequent life stress

  • Female gender

  • Low socioeconomic status

  • Low intelligence

  • Personal history of mental disorders

  • History of childhood adversity

  • Family history of mental disorders

LEARNING & THE DEVELOPMENT OF PTSD

Conditioning Theories

  • Traumatic event (UCS) → Extreme fear and anxiety (UCR)
  • Cognitive, emotional, physiological, and environmental cues associated with the traumatic event become conditioned stimuli
  • Traumatic reminders (CS) → Extreme fear and anxiety (CR).

Cognitive Theories Two key processes in development and maintenance of PTSD:

  1. Disturbances in memory for the event

    • Poorly encoded memories of trauma can become fragmented, disorganized, and lacking in detail

    • Individuals cannot remember event in a way that gives meaning and context

    • May become haunted by these fragments involuntarily triggered by stimuli associated with the event.

  2. Negative appraisals of the trauma and its aftermath (e.g., “I deserve to be raped because I am stupid”).

  • May lead to dysfunctional behavioral patterns that maintain symptoms and prevent changes in the problematic appraisals

MOOD DISORDERS

  • Characterized by massive disruptions in mood and emotions that can cause a distorted out look on life, and impair ability to function

Depressive Disorders Depression (intense and persistent sadness) is the main feature.

Bipolar and Related Disorders Mania (extreme elation and agitation) is the main feature

  • Manic episode – “a distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormally and persistently increased activity or energy lasting at least one week.” (APA, 2013).

MAJOR DEPRESSIVE DISORDER

Diagnosis Criteria “Depressed mood most of the day, nearly every day” (APA, 2013)

  • Loss of interest and pleasure in usual activities

  • At least 5 symptoms for at least a two-week period

  • Symptoms cause significant distress or impair normal functioning and are not caused by substances or a medical condition

    • Major depressive disorder is episodic (symptoms are usually present at their full magnitude for a certain period of time and then gradually diminish)

Symptoms

  • Weight loss or weight gain/increased or decreased appetite

  • Difficulty falling asleep or too much sleep

  • Psychomotor agitation or psychomotor retardation

  • Fatigue/loss of energy

  • Feelings of worthlessness or guilt

  • Difficulty concentrating, indecisiveness

  • Suicidal ideation – thoughts of death, thinking about/planning suicide, suicide attempt

Prevalence

  • Affects around 6.6% of the U.S. population each year and 16.9% of the U.S. population in their lifetime

  • More common among women than men

Comorbidity

  • Comorbid with anxiety disorders and substance abuse disorders

Risk Factors

  • Unemployment

  • Low income

  • Living in urban areas

  • Being separated, divorced, or widowed

SUBTYPES OF DEPRESSION

Seasonal pattern applies to situations in which a person experiences the symptoms of major depressive disorder only during a particular time of year

Peripartum onset (postpartum depression) major depression during pregnancy or in the four weeks following the birth

Persistent depressive disorder (dysthymia) depressed moods most of the day nearly every day for at least two years, as well as at least two of the other symptoms of major depression

  • Chronically sad but do not meet all the criteria for major depression

BIPOLAR DISORDER

  • Involves mood states that fluctuate between depression and mania

BIPOLAR DISORDER

Symptoms of Mania

  • Excessively talkative

  • Excessively irritable

  • Exhibit flight of ideas – talk loudly and rapidly, abruptly switching from one topic to another

  • Easily distracted

  • Exhibit grandiosity – inflated but unjustified self-esteem and self-confidence

  • Show little need for sleep. - Take on several tasks at once

  • Engage in reckless behaviors

Prevalence Onset is typically before the age of 25

  • Affects 1 out of 100 people in the U.S. in their lifetime
  • 36% of these individuals attempt suicide

Comorbidity anxiety disorder and substance abuse disorder

BIOLOGICAL BASIS OF MOOD DISORDERS

Hormones

  • Elevated levels of cortisol (stress hormone) are found in depression

  • Cortisol activates the amygdala and deactivates the prefrontal cortex (disturbances connected to depression)

Neurotransmitters

  • Mood disorders often involve imbalances in neurotransmitters

    • Particularly serotonin and norepinephrine

    • Many medications work by altering balance

DIATHESIS-STRESS MODEL & MAJOR DEPRESSIVE DISORDERS

  • Stressful life events often precede the onset of depressive episodes

COGNITIVE THEORIES OF DEPRESSION

  • Cognitive theories suggest that depression is triggered by negative thoughts, interpretations, self-evaluations, and expectations.

Diathesis-Stress model

  • cognitive vulnerability + stressful life events → depression

COGNITIVE THEORIES OF DEPRESSION

Hopelessness Theory

  • Specific negative thinking style → sense of hopelessness → depression

  • Negative thinking – refers to a tendency to perceive negative life events as having stable (“It’s never going to change”) and global (“It’s going to affect my whole life”) causes

  • Creates view that the life event will have negative implications for the person’s future and self-worth, increasing likelihood of hopelessness

  • Hopelessness - expectation that unpleasant outcomes will occur or desired outcomes will not occur, and there is nothing one can do to prevent such outcomes (seen as the primary cause of depression)

Rumination

  • Distressed mood → Rumination → increased risk and duration of mood

  • Rumination – repetitive and passive focus on the fact that one is depressed and dwelling on depressed symptoms, rather than distracting one’s self from the symptoms or attempting to address them in an active, problem-solving manner

  • Described to explain higher rates of depression in women, who are more likely to ruminate, than in men

SUICIDE

Statistics 90% of those who complete suicides have a diagnosis of at least one mental disorder (most frequently mood disorders)

  • 10th leading cause of death for all ages in 2010 (an average of 105 each day)

  • 4 times higher among males (79% of all suicides) than females

    • Males most commonly use fire arms, females most commonly use poison

Risk Factors

  • Substance abuse problems (10 times greater in individuals with alcohol dependence).

  • Previous suicide attempts.

  • Access to lethal means in which to act (e.g., firearm in the home).

  • Precursors – withdrawal from social relationships, feeling like a burden, engaging in reckless and risk-taking behaviors.

  • Sense of entrapment (feeling unable to escape feelings or external circumstances).

  • Cyberbullying.

  • Suicide of a family member.

  • Serotonin dysfunction.

SCHIZOPHRENIA

Hallucinations perceptual experience that occurs in the absence of external stimulation

  • Auditory hallucinations most common

Delusions beliefs that are contrary to reality

  • Paranoid delusions – belief that other people or agencies are plotting to harm them

  • Grandiose delusions – belief that one holds special power, unique knowledge, or is extremely important

  • Somatic delusions – belief that something highly abnormal is happening to one’s body

  • Thought withdrawal/insertion

Disorganized thinking

  • disjointed and incoherent thought processes

Disorganized or abnormal motor behavior unusual behaviors/movements

  • Catatonic behaviors – decreased reactivity to the environment

Negative Symptoms decreases and absences in certain behaviors, emotions, drives

  • Avolition – lack of motivation to engage in self-initiated and meaningful activity
  • Alogia – reduced speech output
  • Asociality – social withdrawal
  • Anhedonia – inability to experience pleasure

SCHIZOPHRENIA CAUSES

Prevalence Affects 1% of the population

Genetics Risk is 6 times greater if one parent has schizophrenia (even if adopted)

Neurotransmitters

  • Dopamine hypothesis - an overabundance of dopamine or too many dopamine receptors are responsible for the onset and maintenance of schizophrenia

  • Drugs that increase dopamine levels can produce schizophrenia-like symptoms

  • Medications that block dopamine activity reduce the symptoms

    • High levels of dopamine in the limbic system → hallucinations and delusions
    • Low levels of dopamine in the prefrontal cortex → negative symptoms

Brain Anatomy

  • Enlarged ventricles

  • Reduced gray matter in the frontal lobes

  • Many show less frontal lobe activity when performing cognitive tasks

Events During Pregnancy

  • Obstetric complications during birth

  • Mother’s exposure to influenza during the first trimester

  • Mother’s emotional stress.

DISSOCIATIVE DISORDERS

  • Characterized by an individual becoming split off, or dissociated, from their core sense of self
  • Memory and identity become disturbed

Dissociative Amnesia

  • Inability to recall important personal information. - Usually follows a stressful or traumatic experience. - Dissociative fugue – individual suddenly wanders away from home, experiences confusion about their identity, and in some cases may adopt a new identity

Depersonalization/Derealization Disorder

  • Characterized by recurring episodes of depersonalization, derealization, or both

  • Depersonalization - feelings of “unreality or detachment from, or unfamiliarity with, one’s whole self or from aspects of the self”

  • Derealization – a sense of “unreality or detachment from, or unfamiliarity with, the world, be it individuals, inanimate objects, or all surroundings”

Dissociative Identity Disorder (formerly multiple personality disorder)

  • Individual exhibits two or more separate personalities or identities

  • Involves memory gaps for the time during which another identity is in charge

  • Individuals tend to report a history of childhood trauma

  • Adoption of multiple personalities may serve as a psychologically important coping mechanism for threat and danger.

PERSONALITY DISORDERS

  • Characterized by a pervasive and inflexible personality style that differs markedly from the expectations of the individuals culture and causes distress or impairment
  • Begins in adolescence or early adulthood

Prevalence

Slightly over 9% of the U.S. population suffers from a personality disorder

  • Avoidant and schizoid personality disorders are most frequent
  • Antisocial and borderline personality disorder are most problematic

Cluster A

  • Paranoid personality disorder

  • Schizoid personality disorder

  • Schizotypal personality disorder

Cluster B

  • Antisocial personality disorder

  • Histrionic personality disorder

  • Narcissistic personality disorder

  • Borderline personality disorder

Cluster C

  • Avoidant personality disorder

  • Dependent personality disorder

  • Obsessive-compulsive personality disorder

BORDERLINE PERSONALITY DISORDER

  • Characterized by instability in interpersonal relationships, self-image, and mood, as well as marked impulsivity

Symptoms

  • Cannot tolerate the thought of being alone – will make frantic efforts to avoid abandonment or separation

  • Relationships are intense and unstable

  • Unstable view of self – might suddenly display a shift in personal attitudes, interests, career plans, and choice of friends

  • May be highly impulsive and may engage in reckless and self-destructive behaviors

  • May sometimes show intense and inappropriate anger

  • Can be moody, sarcastic, bitter and verbally abusive

Prevalence

  • afflicts 1.4% of the U.S. population.

Comorbidity

  • anxiety, mood, and substance use disorders.

Causes Core personality traits such as impulsivity and emotional instability show a high degree of heritability

  • Many individuals report childhood abuse

ANTISOCIAL PERSONALITY DISORDER

  • Characterized by complete lack of regard for other people’s rights or feelings
  • Diagnosis requires individual to be at least 18 years old

ANTISOCIAL PERSONALITY DISORDER

Symptoms

Repeatedly performing illegal acts=

  • Lying to or conning others

  • Impulsivity and recklessness

  • Irritability and aggressiveness

  • Failure to act in responsible ways

  • Lack of remorse

  • Overinflated sense of self

  • Superficial charmLack ability to empathize

Prevalence

  • Observed in 3.6% of the population
  • More common in males

ANTISOCIAL PERSONALITY DISORDER CAUSES

Genetics

  • Personality and temperament dimensions related to this disorder (fearlessness, impulsive antisociality, and callousness) have a genetic influence

  • Adoption studies suggest antisocial behavior is determined by the interaction of genetic factors and adverse environmental circumstances

Emotional

  • Deficits Individuals with antisocial personality disorder fail to show fear in response to environment cues that signal punishment, pain, or noxious stimulation
  • Show less skin conductance which may indicate emotional deficits

ADHD

  • constant pattern of inattention and/or hyperactive and impulsive behavior that interferes with normal functioning

Symptoms

Inattention:

  • Difficulty sustaining attention

  • Failure to follow instructions

  • Disorganization

  • Lack of attention to detail

  • Easily distracted and forgetful

Symptoms

Hyperactivity:

  • Excessive movement

  • Interrupting and intruding on others

  • Blurting out responses before questions have been completed

  • Difficulty waiting ones turn

Prevalence

  • Occurs in about 5% of children

  • Boys are 3 times more likely to have ADHD than girls

Life Problems

  • Low educational attainment

  • low socioeconomic status

  • unemployment

  • low wages

  • substance abuse problems

  • relationship problems

ADHD CAUSES

Genetics

  • Inattention – 71% heritable

  • Hyperactivity – 73% heritable

Neurotransmitters Dopamine:

  • Genes involved are thought to include at least two that are important in the regulation of dopamine

  • Individuals with ADHD show less dopamine activity in key brain regions (especially those associated with motivation and reward)

  • Medications have stimulant qualities and elevate dopamine activity

Brain Anatomy

  • Studies show smaller frontal lobe volume and less activation when performing mental tasks

  • Frontal lobe inhibits behavior

    • may explain hyperactive, uncontrolled behavior of ADHD

AUTISM SPECTRUM DISORDER

Symptoms

  • Deficits in social interaction (e.g., do not make eye contact, turn head away when spoken to, prefer playing alone)

  • Deficits in communication (e.g., one word responses, difficulty maintaining conversation, echoed speech, and problems using and understanding nonverbal cues)

  • Repetitive patterns of behavior or interests

Prevalence

  • Affects approximately 1 in 88 children in the U.S.

  • 5 times more common in boys

Genetics:

  • Identical twins – 60%-90% concordance rates

  • Fraternal twins – 5%-10% concordance rates

  • Genes involved are those important in the formation of synaptic circuits that facilitate communication between different areas of the brain

Environment:

  • Factors that contribute to new mutations (e.g. pollutants)